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When lower doses work better than higher doses The standard narrative is "higher dose equals more weight loss," but three specific situations reverse that relationship
Do not inject in the same spot repeatedly, as this can cause lipodystrophy, a condition where fat tissue under the skin becomes lumpy or indented
BMC pulmonary medicine , 20 (1), 72
The difference may be because Ozempic is injected weekly, providing more consistent control, while the dose of Rybelsus is once daily
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