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It usually takes approximately 5 months for patients to progress from a low dose of .25 milligrams to the target dose of 2.4 milligrams
Instead of efficient aerobic energy production, the cells are forced into an inefficient anaerobic state, producing excess lactate
Genetic modifiers of somatic expansion and clinical phenotypes in Huntingtons disease highlight shared and tissue-specific effects
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Neurotoxic -amyloid oligomers cause mitochondrial dysfunction-the trigger for PANoptosis in neurons
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