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We propose that TdLN-T TSM cells may represent an early-stage or precursor Tpex population that retains full memory potential, whereas Tpex cells that have resided in the TME for extended periods become progressively restricted to the exhaustion trajectory
It is intended to be administered by intramuscular injection
In preclinical studies, 5-Amino-1MQ provides a powerful tool to dissect the cellular and molecular consequences of NNMT inhibition
(PMID 3169264)
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