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SBP reduction was mostly mediated by weight loss (7794%) in SURPASS-1, -2 and -3, while mechanisms independent from weight loss accounted for most of the tirzepatide benefit on SBP in SURPASS-4 and -5 (57 and 73%, respectively) [77]
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Joza N, Susin SA, Daugas E, et al
Structured stress reduction, even 10 minutes daily, can meaningfully reduce tinnitus perception by downregulating HPA axis activation and auditory cortex hypervigilance
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