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Although the optimal dose of LC supplementation for myocardial infarction is 3 g/day in terms of all-cause mortality [90], even lower LC intake elevates fasting plasma TMAO [16,17,18, 58, 59], which is ten-fold higher than control after 3 months of supplementation [16, 17]

A patient on "the best" GLP-1 medication (by name) who titrates too quickly, skips doses, or stops at the first side effect will have worse outcomes than a patient on "the worst" GLP-1 medication who titrates slowly, stays consistent, and reaches maintenance dose

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