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Given the role of NADPH in the process of phagocytic killing it should be clear that individuals with reduced ability to produce NADPH (such as those with G6PD deficiencies) may also manifest with symptoms that have similarities to those of classically inherited forms of CGD

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It is necessary to select a suitable deprotecting agent according to the reaction conditions and product types, and strictly control the temperature and time of deprotection, and ensure the pH value in the reaction

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