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4 Discussion The pharmacological action of DPP-IV inhibitors has been studied previously in prediabetes ( To the best of our knowledge, this is the first study ever conducted to investigate the relationship between endogenous GLP-1 levels and glycaemic control as well as insulin responses to DPP-IV inhibition in the form of linagliptin therapy in both prediabetes and T2D subjects

doi: 10.1177/0003319709333869 80 RodriguesVSMilanskiMFagundesJJTorsoniASAyrizonoMLSNunezCECet al