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Effect of antiarthritic drugs on the enhanced interleukin-1 (IL-1) production by macrophages from adjuvant-induced arthritic (AA) rats

The results of a recent insightful study implicate the transcriptional control of the Nrf2 gene as a determinant of Nrf2 activity ( K-Ras activates Nrf2 transcription through the Mek-Erk-Jun signaling pathway and reduces the ROS levels in primary fibroblasts

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