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In addition to reducing appetite through GLP-1 and GIP activity, its glucagon action helps the body burn stored fat and increase energy expenditure
2.7 G protein activation assay by Nb37 BRET A construct encoding SNAP-GLP-1R with a C-terminal nanoluciferase was generated in house by PCR cloning of the nanoLuciferase sequence from pcDNA3.1-ccdB-Nanoluc (a gift from Mikko Taipale
This is the defining feature of a secretagogue , and it is central to how these peptides are discussed
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