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Why is NNMT considered a metabolic target

Medications for diabetes and weight loss included semaglutide (sold under the brand names Ozempic and Rybelsus for diabetes, and Wegovy for weight loss), dulaglutide (sold as Trulicity), liraglutide (Victoza and Saxenda, among others), empagliflozin (Jardiance, among others), and metformin (Glumetza, among others)

The company is exploring alternative methods of administering GLP-1 medications beyond injectables, with the goal of achieving scalable production to reach a wider population, says Karla Alczar, President and General Manager, Lilly Latin America, during Mexico Health Summit 2025.

Because the absorption profile differs, directly converting an injectable dose to an ODT dose is not straightforward