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A cysteine-specific lysosomal transport system provides a major route for the delivery of thiol to human fibroblast lysosomes: possible role in supporting lysosomal proteolysis
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In addition to its role as a critical blood buffer, phosphate is required in the biosynthesis of cellular components, such as ATP, nucleic acids, phospholipids, and proteins, and is involved in many metabolic pathways, including energy transfer, protein activation, and carbon and amino acid metabolic processes
The primary pharmacokinetic difference between the routes is therefore kinetic rather than total exposure: IM produces sharper, faster peaks while SubQ produces slower, more sustained plasma profiles
