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Resistance exercise, with or without adjunctive protein supplementation, is the only intervention with good evidence of efficacy for the prevention and treatment of sarcopenia [11, 12], but not all individuals with sarcopenia are willing or able to participate in such training
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Severe, persistent cramping that doesn't respond to conservative measures warrants medical evaluation to rule out underlying electrolyte disorders
or 2 M in vitro) for all Nrf2-dependent endpoints
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