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Two recent drugs, that were designed to target liver lipoprotein homeostasis, have been approved for use in humans
In research contexts, subcutaneous GHK-Cu injection is being explored for its systemic effects particularly its potential to deliver anti-inflammatory, tissue-regenerative, and gene-expression-modulating effects to tissues beyond the skin, including muscles, joints, internal organs, and the central nervous system
It also has anti-inflammatory effects, decreasing the pro-inflammatory cytokines TNF-, IL-6, MCP-1 and IL-1 in serum and liver, and inhibiting the TLR4/NFkB pathway
The big elephant in the room is the medications are too expensive. The GLP-1 market has ballooned in recent years, as drugmakers race to find new variants and thereby seize a piece of a lucrative industry
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