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Additionally, macrophages enhance ECM deposition which increases the release of proinflammatory cytokines and results in a vicious cycle that perpetuates the inflammatory state [97]
Glutathione is the anchor for brightening: the bodys master antioxidant inhibits tyrosinase, the enzyme that drives melanin production, which is the mechanism behind its use as a brightening and antioxidant support, not a disease treatment
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