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identified mitophagy as an intrinsic vulnerability in CRC cells subjected to statin treatment, revealing how disruption of mitochondrial homeostasis, shaped by distinct metabolic contexts, leads to cell death and therapeutic sensitivity [103] Spatial heterogeneity across colorectal tumor sites underlies distinct metabolic phenotypes [104]

While more experienced brands may eventually move toward fully custom formulations and larger production scales, beginning with a structured private label system often provides the practical foundation needed to test a product concept and start building a brand presence in the market