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A continuacin, una protena transportadora, llamada carnitina-acilcarnitina translocasa, situada en la membrana mitocondrial interna, transfiere la acilcarnitina a la matriz mitoncondrial, donde la carnitina palmitoiltrasnferasa II (CPTII) escinde la carnitina y une al cido graso una molcula de CoA de la matriz
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