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Fragmentation pathways may involve cleavage at amide bonds, producing characteristic fragment ions corresponding to partial backbone structures
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That potency is its appeal and its caution, which is why it's reserved for supervised use
A pharmacology that keeps amylin receptors tonically engaged, day and night, may reproduce amylins central appetite effects (which appear to tolerate sustained stimulation reasonably well) while behaving quite differently at the level of the stomach, where continuous braking could invite adaptive counter-regulation
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