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By comparison, orlistat (Xenical) produced approximately 3-4 kg more weight loss than placebo over 12 weeks in its pivotal trials, and GLP-1 agonists produce 8-15 kg more than placebo
Evidence from studies published in Frontiers in Endocrinology underscore the efficacy of these peptides in improving physical performance and mitigating fatigue
For mature scars, other interventions may be more appropriate, though BPC-157 could potentially support remodeling if used in conjunction with treatments that re-activate healing (such as microneedling or laser resurfacing)
Secondary endpoints in trials include reductions in waist circumference , visceral fat mass, appetite scores, and daily caloric intake
