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They also confirmed that concurrent treatment with JHU083 and anti-PD-1 checkpoint inhibitor improved the antitumor effects compared with anti-PD-1 treatment alone, suggesting the presence of metabolic plasticity between cancer cells and effector T cells, which could be exploited as a metabolic checkpoint for cancer immunotherapy 200
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Los agonistas del receptor de GLP-1, modificados bioqumicamente para una mayor potencia y una accin sostenida, se utilizan con xito en la prctica clnica para el tratamiento de la diabetes tipo 2, y varias farmacoterapias basadas en GLP-1 se encuentran en evaluacin clnica para el tratamiento de la obesidad
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