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This cellular alteration further raises doubts about the efficacy and reproducibility of stem cell therapy, particularly when isolating stem cells from elderly patients for regenerative purposes

FG: Formal analysis, Funding acquisition, Project administration, Resources, Validation, Visualization, Writing original draft

Then, although at the time evaluated here it was not observed, it is possible that peripheral NGF activates the NGF/TrkA signaling pathway in brain endothelial cells and enables the entrance of the sulfhydryl AAs L-cys/L-cys2 into the brain parenchyma and the subsequent secretion of NGF in the brain, where it plays a critical role in the antioxidant response via the NGF/TrkA pathway (Figure 6) in neurons and glial cells

Many flavonoids have been shown to possess promising antimicrobial capacity against H