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Tirzepatide and its cousins encourage weight loss by regulating appetite, leading to significant, and often rapid, changes in body composition

This would be a significant shift from the current weight-loss exclusion

Research in heart failure with preserved ejection fraction (HFpEF) shows improvements in exercise capacity and heart failure symptoms, expanding potential applications beyond diabetes and obesity

Liraglutide works in a few different ways: It acts on parts of the brain that regulate hunger, reducing your appetite It lowers blood sugar after eating and prevents blood sugar spikes, reducing cravings for sugary and high-calorie foods It delays the rate at which food leaves your stomach (gastric emptying), increasing fullness [1] Together, these effects make it easier to eat balanced meals, smaller portions and fewer calories, promoting weight loss