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Since its not made in the body, it has to come from an external source via diet and/or supplementation

Disruption of neuronal nitric oxide synthase dimerization contributes to the development of Alzheimers disease: involvement of cyclin-dependent kinase 5-mediated phosphorylation of neuronal nitric oxide synthase at ser(293)

Although your doctor may put aside their concerns if/when you explain that you have been supplementing with vitamin B12, it's not outside the realm of reason that your doctor may still want to bring you in to rule out serious illness

Patients report a significantly better tolerance compared to traditional options, making it suitable for a broader demographic, including those with pre-existing health concerns