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According to the results published in The New England Journal of Medicine (NEJM), participants taking tirzepatide achieved average weight reductions of 16.0% (35 lb
Epidemiological evidence from large cohort studies The strongest population-level evidence comes from a study published on medRxiv that compared allodynia incidence between GLP-1 receptor agonist users and users of bupropion-naltrexone, an alternative weight management medication
Peptides 2023;162:170955.ArticlePubMed 109
As the field evolves, its crucial for healthcare leaders and organizations to stay agile, adapt to new trends, and focus on what matters most for patients and providers, namely: GLP1s are now firstline therapies: Adoption has accelerated from just 3% in 2021 to more than 23% in 2025, displacing longstanding generics like metformin
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