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Six RCTs utilized matching placebos [26-29,31,35], four used insulin [33,34,36,37], two employed GLP-1RA [30,32], and one trial included both placebo and GLP-1RA in the control groups [25]
323,324 Lactate-derived lactylation is consequently involved in modulating inflammation in RA
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They may recommend a dose adjustment, a brief pause followed by restart, or complementary approaches
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