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Key Takeaway Methylation influences many of the bodys most important biological processes, from regulating genes and repairing DNA to producing neurotransmitters and maintaining cardiovascular and brain health

It introduces confounding variables that make drawing any real conclusion impossible

Tirzepatide activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors, creating additive appetite suppression and insulin secretion compared to semaglutide alone

Early lab data shows that NNMT inhibition helps preserve nicotinamide, a compound the body uses to form NAD, which supports cell energy