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When adverse effects occurred, they were typically mild and transient, with the most common being mild to moderate headaches (similar frequency to placebo groups), minor injection site reactions (redness, slight swelling), and gastrointestinal effects at higher oral doses (nausea, diarrhea)
B12 is supplied as methylcobalamin, the stable form immediately used by the body
It promotes angiogenesis, the formation of new blood vessels that deliver nutrients to damaged tissue
At the same time, they are not a substitute for large, long-term human clinical trials
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