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Such vascular responses are particularly relevant in experimental models of ischemia, where enhanced circulation contributes to tissue preservation and recovery.(22) In addition to its effects on vascular growth, it has been associated with regulation of vascular tone through interactions with nitric oxidedependent signaling mechanisms
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It is studied in preclinical models to investigate combined tissue repair strategies, synergistic effects on wound healing, musculoskeletal recovery, and gastrointestinal protection
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