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For instance, in one interesting study, PLGA NPs were shown to be active before the occurrence of a rise in blood pressure (shear stress), providing the release of the anti-thrombolytic agent t-PA, which is the gold standard medication for treating ischemic stroke or myocardial infarction [88]

The same abstract framing of the immune system also applies to the nervous system, particularly the CNS, which processes information from the external and internal worlds and commands reactions to external and internal stimuli to maintain homeostasis, allostasis, and survival