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Obesity, as a global chronic disease characterized by excessive fat accumulation, affects the health of approximately 650 million people and is associated with an increased risk of multiple metabolic complications, such as Type 2 diabetes and non-alcoholic fatty liver disease, as well as cardiovascular diseases and mechanical issues, including osteoarthritis and obstructive sleep apnea
In some cases, the blockage can result in bladder failure requiring a permanent catheter, kidney failure, bladder stones, and recurrent urinary infections
The peptide demonstrates a capacity to counteract damage caused by neurotoxic agents (dopamine system disruptors and excitotoxic compounds) in animal studies
Methods: We reanalyzed published data from liver sc-RNAseq and generated signature matrices with specific genes for each of the non-parenchymal cells populations
