The National Institute on Alcohol Abuse and Alcoholism, for instance, is working with the University of North Carolina at Chapel Hill on a Phase II trial testing semaglutide in people with alcohol use disorder
68,69 Investigators have noted lower GSH concentrations to be associated with the combination of advanced age and increased risk of chronic diseases such as chronic renal failure, malignant disorders, diabetes, alcoholism, Parkinson's disease, and cataract formation
There are some potential reasons for these controversy including small sample size, unavailability of some patient-related data including smoking and drinking status, age and sex, and finally, a lower linkage disequilibrum (LD) in African population compared to Chinese population [35]
This distinction matters because people often confuse the two