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Further studies with a larger cohort are necessary
Samples and standards were serially diluted in assay buffer and tested for cAMP accumulation in CHO cells expressing human GLP-1R as described above
Notably, semaglutide treatment was associated with a reduction in proteins upregulated in neuropathic pain and an increase in proteins typically downregulated in such conditions, further supporting the potential therapeutic benefits of semaglutide in managing neuropathic pain [67]
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