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Then, once in the extracellular space, GSH is cleaved by -Glutamyl-Transferase (GGT), which is also known as a poor prognostic factor for cancer patients (34)
The Lancet (2021) 4
In vivo xenograft model experiments have shown that injection of RGD-modified sEVs carrying miR-484 can induce vascular normalization, thereby sensitizing cancer cells to chemotherapy-induced apoptosis [211]
Phase II takes these highly reactive, dangerous intermediates and binds (conjugates) them to endogenous molecules to neutralize them
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