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The PKC pathway becomes activated through hyperglycemia-induced increases in diacylglycerol (DAG), with PKC- and PKC- isoforms particularly implicated in stimulating NOX activity while inhibiting AMPK-mediated antioxidant responses (Geraldes and King, 2018)
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Theres a possible increase in the risk of gallbladder disease in people taking semaglutide for more than six months
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