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According to a recent review of pre-clinical and clinical studies, GLP-1 receptors have been identified in testicular tissue, including Leydig cells (which produce testosterone), Sertoli cells (which help support sperm development), and even sperm cells themselves
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Besides the known CVD impact, GLP-1RAs' benefit to SA offers new insights for multi-risk-mitigation strategies and breaks the vicious cycle of cardiometabolic dysfunction at multiple points
Weight began coming off well before then, and the trial record gives us a reasonable picture of the intermediate milestones, but the curve in these studies keeps descending for the better part of a year before it flattens
