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Elevated GGT degrades glutathione (GSH), releasing harmful hydrogen sulfide and reducing antioxidant and mitochondrial activity 63 64 35
doi.org/10.3389/fphar.2021.627533 Chang, C
Likewise, the origin of the glutathione that accumulates in this compartment remains unclear, as does whether external factors, such as glutathione-rich diets or direct intake of this compound as an antioxidant supplement, might influence its levels in the tumour microenvironment
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