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In addition to its pro-differentiating actions, nicotinamide promotes neuronal survival, especially in oxidative stress environments, through various pathways, such as maintenance of protein kinase B (akt)-dependent phosphorylation of forkhead transcription factor (FOXO3a)

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Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-kappaB activity in hypoxic tumor cells

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