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As a result, the activity of the electron transport chain (ETC) is hindered, decreasing ATP production during oxidative phosphorylation [8]
Similar to IL-4, IL-13 has anti-inflammatory and reparative effects, which can promote the polarization of macrophages toward the M2 phenotype and enhance their phagocytic capacity, thereby clearing damaged tissue debris and creating conditions for muscle repair (195)
Furthermore, GCLC-KO mouse will serve as a useful tool to investigate the molecular mechanisms underlying neurodegeneration and in the development of new treatment strategies to address neurodegenerative diseases
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