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Heat shock protein (hsp)-based chaperone therapies (Arimocromol) and histone deacetylase inhibitors rescue misfolded NPC1 mutants, which upon drug treatment, reach LE/Lys to correct the NPC cholesterol phenotype [5, 6]
2017 Feb;67(2):280-284
The critical difference between the two forms comes down to a single molecular addition: the Drug Affinity Complex (DAC)
The burden of COVID as well as available treatments, resources and research have revealed significant disparities between affected communities with different income
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