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For example, the Wegovy prescribing information notes, Coadministration with other semaglutide-containing products or with any other GLP-1 receptor agonist is not recommended. Similarly, the Zepbound prescribing information notes, Coadministration with other tirzepatide-containing products or with any GLP-1 receptor agonist is not recommended. Side effects of taking semaglutide with tirzepatide Semaglutide and tirzepatide have long lists of potential side effects

For the most part, hypotheses related to these factors are not entirely new (113, 114, 126), but recent developments across several fields generate renewed interest (139)

PMID: 32200730, PMCID: PMC7428633, DOI: 10.1161/jaha.119.015033