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Additionally, we summarize the current clinical status of therapeutic agents targeting these apolipoproteins and its future potential

(10) DSIP and Endocrine Regulation DSIP has been posited to interact with certain hormonal messengers typically released during sleep

Traditionally used as an anti-diabetic agent, Metformin was not only found to decrease HIF-1 expression of TMZ-resistant GBM cells in combination with TMZ but also, when used alone, was able to reverse hypoxia-induced genes by reducing the oxygen consumption rate (156)

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