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66 determined that binding interactions between podoplanin on the surface of TAMs and galectin 8 (GAL8) expressed by LECs can promote pro-migratory integrin 1 activation, thereby enabling TAMS to migrate toward and adhere to LECs, facilitating TAMmediated lymphangiogenesis

The researchers assessed markers related to proliferation, regeneration, aging, apoptosis, and extracellular matrix remodeling

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Pratibha Natesh said the findings support treating underlying conditions rather than relying on hormone therapy