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Common challenges target: composition claim scope (sequence variants, analogs, and pegylated or acylated differences), method-of-treatment claims (carve-outs around dosing regimens, endpoints, or indication), formulation and device (stability systems, delivery mechanics, and concentration/vehicle definitions), manufacturing process (where competitors alter cell lines or purification steps to avoid manufacturing claim coverage)

For detailed information on the GLP-1 comparison, see how does retatrutide work and retatrutide vs tirzepatide