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A Caco-2 bidirectional transport assay showed an apparent permeability (P app ) of 34.2 10 6 cm/s from apical to basolateral and 45.2 10 6 cm/s from basolateral to apical, with an efflux ratio of 1.33, indicating high permeability and no significant efflux
AOD-9604 vs GLP-3 RT GLP-3 RT (retatrutide) adds a third receptor target glucagon on top of the GIP/GLP-1 combination, representing the broadest incretin-pathway approach among compounds referenced in this comparison
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