surmount-1 tirzepatide trial obesity without diabetes for the Maintenance of Body Weight Reduction: Rationale, Design, and Baseline Characteristics of SURMOUNT‐MAINTAIN - Horn - 2025 - Tirzepatide vs. Semaglutide for Weight

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The chronic low-grade inflammatory state that results, sometimes called inflammaging, creates a systemic environment that progressively impairs insulin sensitivity, disrupts lipid metabolism, and elevates cardiometabolic risk [4,5]

By contrast, the intake of carbohydrates (both in grams per day and as a percentage of total calories), fiber, calcium, iron, magnesium, potassium, choline, and vitamins A, C, D, E, and K was significantly less than the DRI