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Glucaric acid and ribonic acid had the most significant positive correlation with each other, and there were also highly positive correlations between L-acetylcarnitine and L-carnitine, and between taurine and glutathione (Table 3)
In a previous study that matched populations from the Trial to Evaluate Cardiovascular and Other Long-term Outcomes with Semaglutide in Subjects with Type 2 Diabetes (SUSTAIN 6) and Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND) cardiovascular outcome trials using the propensity score method, semaglutide reduced 3-point MACE (cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke) by 26% compared to dulaglutide, although the reduction was not statistically significant (hazard ratio [HR], 0.74
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