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Voluntary running exercise alters microbiota composition and increases n-butyrate concentration in the rat cecum
Frontiers in Microbiology
The underlying mechanisms may involve naringins capacity to modulate the activity of enzymes involved in cholesterol synthesis and catabolism, such as HMG-CoA reductase
While it makes achieving sustained systemic levels difficult, its perfectly suited for triggering rapid signaling cascades or for localized topical use
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