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S3 show the results for the outcome MACE: both GLP-1RA and SGLT-2 inhibitors were associated with a lower risk for MACE (13% and 11%, respectively) as compared with placebo, and a lower risk for MACE as compared with DPP-4 inhibitors (12% and 11%, respectively)
Ferroptosis is a novel form of programmed cell death characterized by iron-dependent oxidative damage, lipid peroxidation, and the accumulation of reactive oxygen species (Zuo et al., 2022)
Lack of approval means lack of long-term safety data beyond 48 weeks, not proven danger
Hair follicles serve as reservoirs of stem cells that contribute to re-epithelialization
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