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Despite a number of mechanisms have been discussed in this review, most of the ROS-induced signaling targets are yet unknown
Cell 187 , 37893820 (2024)
Transferrin receptor 1 (TfR1), a well-known regulator of cellular iron that internalizes the transferrin-bound iron, plays a significant role in ferroptosis, and ROS induction has been shown to enhance TfR1 protein levels and serves as a marker of ferroptosis 8
After reconstitution, refrigerate at 28C and use within 30 days
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