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Particular concerns exist for those with: Type 2 diabetes or pre-diabetes , due to opposing and unpredictable glycaemic effects Cardiovascular disease , given the potential for heart rate changes and fluid retention associated with GH Active malignancy , as GH stimulation is contraindicated in this setting Pregnancy or breastfeeding neither agent should be used during pregnancy or whilst breastfeeding

As a response, muscles use glutathione to counteract the harmful oxidative effects

Testosterone requires a prescription in Canada but is available through hormone optimization clinics and telemedicine services