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In the STEP 1 trial, semaglutide 2.4 mg produced a mean body weight reduction of 14.9% over 68 weeks but the quality of that weight loss, including preserving lean mass and building healthy habits, determines how maintainable the result is
Four-week titration steps (or longer if needed) reduce nausea and improve adherence
Xerostomia may be alleviated by use of saliva substitutes, alcohol free mouthwashes, SLS-free toothpastes and other interventions such as lozenges and gum
Within biological systems iron can react with oxygen to catalyze the formation of the toxic hydroxyl radical via the Fenton reaction
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